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» Faculty of Medicine » Home » Somatic IL4R Mutations in Primary Mediastinal Large B-cell lymphoma lead to constitutive JAK-STAT signaling activation

Somatic IL4R Mutations in Primary Mediastinal Large B-cell lymphoma lead to constitutive JAK-STAT signaling activation

By stacy hung on April 27, 2018

Our work on IL4R mutations in PMBCL has been published in the Blood!  This work, which was led by Elena Viganò, establishes IL4R mutations as novel driver alterations and provides a strong preclinical rationale for therapeutic targeting of JAK-STAT signaling in PMBCL.

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Steidl Lab
Lymphoid Cancer Research
675 W 10th Avenue, Room 12-110
Vancouver, BC Canada V5Z 1L3
Tel 604 675 8046
Website steidllab.med.ubc.ca
Email csteidl@bccancer.bc.ca
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